https://her-2signaling.com/ind....ex.php/roles-of-four
We now have successfully identified and characterized a unique modified base called 2-methylthio-methylenethio-N6 -(cis-4-hydroxyisopentenyl)adenosine, which is present at position 37 in a few tRNAs. We also revealed that this brand-new modified adenosine hails from the known 2-methylthio-methylenethio-N6 -(isopentenyl)adenosine nucleoside by a catalytic cycle associated with the tRNA-diiron monooxygenase, MiaE, present in Salmonella typhimurium.Spiny keratoderma (SpK) is an u