https://www.selleckchem.com/pr....oducts/Tranilast.htm
Th cells (helper T cells) have multiple functions in ( ) infection. Inducible co-stimulator (ICOS) is induced and expressed in activated T lymphocytes, which enhances the development of B cells and antibody production through the ICOS/ICOSL pathway. It remains unclear about the role and possible regulating mechanism of ICOS Th cells in the spleen of -infected C57BL/6 mice. C57BL/6 mice were infected with cercariae of through the abdomen. The expression of ICOS, activation markers, and the cytokine production on CD4 ICOS Th cells were