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However, discover still scarce information on the mobile and molecular changes provoked by IBU and OTC on aquatic photosynthetic microorganisms as microalgae, much more when we reference their particular possible combined poisoning. To evaluate the cyto- and genotoxicity provoked by IBU, OTC and their binary combo on Chlamydomonas reinhardtii, a flow cytometric panel had been done after 24 h of single and co-exposure to both pollutants. Assayed parameters were cell vitality, metabolic