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These findings suggest that MS participants had enhancement of attention and cognitive control on untrained tasks following WM training that was similar to the effects that were observed in controls. In contrast, only the control group exhibited pretest-to-posttest enhancement of a late positive potential on the Spatial 3-back, as well as enhancement of P3 amplitude across all of the untrained outcome tasks. These latter findings suggest that there may be potential limitations in the neural plasticity induced by WM training in MS. Overa