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d on ClinicalTrials.gov (NCT03544112) on June 01, 2018 https//clinicaltrials.gov/ct2/show/NCT03544112 . Accurate diagnosis of high-grade branching type intraductal papillary mucinous neoplasms (BD-IPMNs) is challenging in clinical setting. We aimed to construct and validate a nomogram combining clinical characteristics and radiomic features for the preoperative prediction of low and high-grade in BD-IPMNs. Two hundred and two patients from three medical centers were enrolled. The high-grade BD-IPMN group comprised patients with high-grade