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D on allergic sensitization.Polymalate (PMA) produced by the whole genome duplicated strain Aureobasidium melanogenum OUC had a high molecular weight (Mw) of 3.9 × 105 Da while the Mw of PMA produced by A. melanogenum ATCC62921 was 3.8 × 104 Da. Therefore, the purified PMA produced by A. melanogenum OUC could form hydrogel and film and the precipitated Ca2+-PMA looked like noodle whereas the purified PMA produced by A. melanogenum ATCC62921 could not form such a hydrogel and a film and the precipitated PMA was powder-like. The h