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ADHD and Sleep Medication People with ADHD struggle to get sleep. They feel agitated when they finally go to sleep, and many wake up frequently throughout the night. Objective measures like polysomnography or actigraphy reveal that children suffering from ADHD have longer sleep onset latency, lower sleep efficiency and shorter real sleep time than controls. Nevertheless the objective measures of sleep improve with treatment for MPH. 1. Medicines to ease restlessness Being diagnosed with ADHD can make it difficult to sleep and get an adequate a