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Our results suggest that genetic variants identified from BPH GWAS can identify pharmacologic targets for BPH treatment. Our results suggest that genetic variants identified from BPH GWAS can identify pharmacologic targets for BPH treatment.Sexually antagonistic coevolution is predicted to lead to the divergence of male and female genotypes related to the effects of substances transferred by males at mating on female physiology. The outcome of mating should thus depend on the specific combination of mating genotypes. Although mating has b