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The online version contains supplementary material available at 10.1007/s10336-021-01893-x. The online version contains supplementary material available at 10.1007/s10336-021-01893-x. Optimum timing is crucial to avoid negative outcomes of weaning. We aimed to investigate predictive values of diaphragmatic thickening fraction (DTF), diaphragmatic excursion (DE), and anterolateral lung ultrasound (LUS) scores in extubation success and compare with rapid shallow breathing index (RSBI) in patients extubated under traditional parameters. Patients undergoing mec