https://cxcrsignal.com/index.p....hp/the-5th-dimension
The primary manifestations of liver injuries were apoptosis and edema of hepatocytes. In our earlier analysis, we found the activation of Kupffer cells (KCs) which enhanced IL-6 can aggravate liver cell apoptosis in TCE sensitized mice. But, the process of IL-6 in liver problems induced by TCE wasn't clear. This study explored the big event of IL-6/STAT3 signal pathway from the TCE caused apoptosis of liver cellular. We established a TCE sensitized BALB/c mouse model with a KCs inhibitor GdCl3, we unearthed th