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Consequently, we investigated conserved miRNA profiles in cynomolgus macaques by homology researching and little RNA sequencing. In total, 1,455 high-confidence miRNA gene loci were identified, 408 of that have been also confirmed by RNA sequencing, including 73 brand new miRNA loci reported in cynomolgus macaques the very first time. Evaluating miRNA appearance with age, we found a positive correlation between series preservation and appearance amounts during miRNA evolut