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[Correction added on 14th November 2020, after first online publication "The last phrase regarding the abstract area was modified."].Tetrabutyl phosphonium sulfate ([TBP]2SO4), as novel room-temperature ionic liquid (RTIL), ended up being synthesized by a simple affordable method, characterized by 1H, 13C, 31P NMR and FT-IR spectrophotometry. The newly prepared catalyst was made use of as a competent catalyst in certain four multicomponent reactions (4MCRs) e. g., to synt