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Arterial blood pressures were significantly lower in R60 treatment from 75 up to 120 minutes post epidural injection. Analgesia was considered moderate for both treatments lasting longer with romifidine at 60 μg/kg. Epidurally administered romifidine and morphine combination in horses produces dose-dependent sedation, arterial hypotension, and antinociceptive effects.The microorganisms in the cecum of donkeys share similar functions as those in the rumen of cattle. Transformation of the cecal microenvironment by probiotics plays an impo