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The cell viability and apoptotic effectation of Ad-SGE-REIC were assessed in vitro utilizing an MTT assay and Hoechst staining. The anti-tumor effect in vivo had been evaluated in a mouse xenograft model. We also evaluated the healing ramifications of Ad-SGE-REIC therapy with cisplatin. Cell signaling was considered by Western blotting. OUTCOMES Ad-SGE-REIC reduced cell viability, and caused apoptosis in biliary cancer cellular outlines through the activation of the c-Jun N-terminal kinase pat