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Evaluation of cardiopulmonary exercise testing (CPET) slopes such as [Formula see text] (cardiac/skeletal muscle function) and [Formula see text] (O delivery/utilization), using treadmill protocols is limited because the difficulties in measuring the total work rate ([Formula see text]). To overcome this limitation, we proposed a new method in quantifying [Formula see text] to determine CPET slopes. CPET's were performed by healthy patients, (n = 674, 9-18year) 300 female (F) and 374 male (M), using an incremental ram