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A novel chemo-sensor predicated on triphenylamine derivative Probe-TPA for thiophenols (C6H5SH, p-NH2-C6H4SH, p-OH-C6H4SH) recognition was provided in this work. The target dye Probe-TPA exhibited large selectivity and extremely fast reaction toward thiophenols in DMSO/PBS buffer (5/5, v/v) answer when you look at the existence of other competitive types (such as for instance K+, Na+, Ni2+, Fe3+, S2-, HS-, SO42-, SO32-, NaClO, H2O2, GSH, Cys, Hcy, etc.). The se