https://www.selleckchem.com/pr....oducts/iacs-010759-i
Meningioma is the most common primary brain tumor. Most meningiomas are benign; however, a subset of these tumors can be aggressive, presenting with early or multiple tumor recurrences that are refractory to neurosurgical resection and radiotherapy. There is no standard systemic therapy for these patients, and post-surgical management of these patients is usually complicated due to lack of accurate prediction for tumor progression. In this review, we summarise the crucial immunosuppressive role of checkpoint regulators, i