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The median HER2/CEP17 ratio cut-off price ended up being 5.0 ± 5.0 (min-max = 1.0-14.. When it comes to total population, the median pCR rate was 48% utilising the arbitrary result design. The research had been classified in quartiles as follows ≤2 (Class 1); 2.1 to 5.0 (Class 2); 5.1 to 7.0 (Class 3); and 7.0 (Class 4). After grouping, the pCR rates were 33%, 49%, 57%, and 79%, respectively. Whenever we excluded the analysis by Greenwell et a