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Formalin-fixed paraffin-embedded tissue from tumour biopsies will be analysed only in the case group. Molecular and serological analyses will be performed to evaluate the presence and role of HPV in the development of head and neck cancer. ETHICS AND DISSEMINATION This project was approved by the research ethical committee of the proposing institution (Hospital Moinhos de Vento, number 2.852.06. Ethical approval from the collaborators is currently under evaluation and is not yet complete. The results of this study will be presented at m
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