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GG adjusted OR = 0.79, 95%CI = 0.64-0.97, and P = 0.026; AA/GA vs. GG adjusted OR = 0.81, 95%CI = 0.66-0.99, and P = 0.037; ≥59 years GA vs. GG P = 0.036; never alcohol consumption GA vs. GG P = 0.013; GA/AA vs. GG P = 0.016; body mass index (BMI) ≥ 24 kg/m2 GA vs. GG P = 0.030; GA/AA vs. GG P = 0.041). The BTLA rs16859629 polymorphism increased the risk of the development of squamous cell carcinoma (CC vs. TT adjusted OR = 9.85, 95%CI = 1.37-71.03, and P = 0.023; CC vs. TT/TC adjusted OR = 9.55, 95%CI = 1.32-68.66, and P = 0.025). Taken