https://www.selleckchem.com/pr....oducts/Adrucil(Fluor
Wide surgical resection with tumor-free margins is important for a favorable prognosis. This study examined whether the immunomodulator fingolimod (FTY72 could alleviate renal ischemia/reperfusion (I/R)-induced lung injury and explored the potential mechanisms. Renal I/R was established in a rat model, and FTY720 (0.5, 1, or 2 mg/kg) was injected intraperitoneally after 15 minutes of ischemia. Pro-inflammatory cytokine levels, oxidative stress, apoptosis, and the mRNA expression of the sphingosine-1-phosphate (S1P)-relat