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Unlike males, for females, no increased risk had been found for cancer for the thyroid gland. In conclusions, levothyroxine treatment had been connected with an excess cancer risk, including many different types of cancer tumors, particularly among women. Our outcomes need confirmation by various other scientific studies, but levothyroxine is recommended become prescribed only on authorized indications. OBJECTIVE Pre-eclampsia (PE) is a significant reason behind maternal morbidity and mortality, b