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We demonstrate that it is possible to rationally incorporate both an isolated flat band and the physics of zero dimensions (0D), one dimension (1D), and two dimensions (2D) in a single 2D material. Such unique electronic properties are present in a recently synthesized 2D covalent organic framework (COF), where "I"-shaped building blocks and "T"-shaped connectors result in quasi-1D chains that are linked by quasi-0D bridge units arranged in a stable 2D lattice. The lowest unoccupied conduction band is an isolated flat band, and electron-