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1% of the triple-negative and HER overexpression tumors. The increase in IGF-IR was significant ( 0.001) in 41.9% of luminal tumors A and B. ROC analysis showed that EGFR had a higher predictive performance (AUC = 0.891) than IGF-1R (AUC = 0.6. The Kaplan-Meier analysis indicated that only the high expression of EGFR was associated with a decreased probability of survival for patients, what did not happen with IGF-1R. Our results suggest that EGFR and IGF-1R expression patterns associated with the clinical characteristics of patien