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Estimated vBMD for the cortical and cancellous regions were affected by voltage and kernel but not by current. Our study demonstrated that there exists a significant variation in the estimated vBMD values obtained with different scanning acquisitions. In addition, the large noise differences observed utilizing different scanning parameters could have an important negative effect on small subregions containing fewer voxels.A carbon dot-based fluorescence turn-on sensor for hydrogen peroxide (H2O2) with a photo-induced electron transfer mechanism was