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Consequently, identifying unique systems that advertise real human uterine smooth muscle (hUSM) relaxation is really important to enhancing medical management of PTL. Here, we aimed to ascertain if an extraocular opsin receptor (OPN 3,4,5) system is expressed in expecting hUSM and to define how photo-mediated leisure of pre-contracting hUSM could be facilitated by additional application of light. Translational studies were performed with hUSM from healthy late pregnancy patients (n = 8) and no