https://www.selleckchem.com/pr....oducts/avelestat-azd
84%) had PMS2 and MLH1 deficiency. In total, 16 patients (25.81%) had MSH2 and MSH6 deficiency. A total of 5 patients (8.06%) showed simply PMS2 deletion and 5 patients (8.06%) showed simply MSH6 deletion. In total, 2 patients (3.23%) showed concurrent loss of PMS2, MLH1 and MSH2. No significant difference were found ( 0.05) in the above factors among dMMR CRC patients with different MMR proteins deletions. Our results show that dMMR status may be more likely exist in female and younger (≤55 years) patients with a greater
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