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Stimulant Vs Non Stimulant ADHD Medication The most frequently prescribed medication used by healthcare providers to treat ADHD is stimulants. They focus on specific chemicals in the brain, such as dopamine and norepinephrine to treat symptoms such as impulsivity and lack of attention. Nonstimulant medications are an alternative treatment for those who aren't able to respond to stimulants. They also have less adverse effects. They target different neurotransmitter