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ngs indicate an unchoreographed process of diverse T-cell clones directed against numerous non-self antigens found in the allograft. Donor-reactive T-cells are enriched in the kidney allograft during a TCMR episode, and dominant tissue clones are also found in the blood. Clinicaltrials.gov NCT 03422224 (https//clinicaltrials.gov/ct2/show/NCT03422224). Clinicaltrials.gov NCT 03422224 (https//clinicaltrials.gov/ct2/show/NCT03422224).Nuclear factor kappa B (NF-κ is a critical transcription factor involved in regulating cell activation, i