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Methods are presented for the preparation of Nb stock solutions in hydrofluoric acid and Zr stock solutions in sulphuric acid. It is shown that multi-Ci productions of 88Y are feasible at a 70 MeV cyclotron facility, suitable for the needs of fracking applications. In addition, 88Zr/88Y generators can provide 88Y with very high specific activity, suitable for labelling of biomolecules. LA-UR-20-24305.Over the last decade one of the most significant technological advances made in the field of radiation detectors for nuclear medicine was th