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Portal vein thrombosis (PVT) is a relatively frequent event in patients with cirrhosis. Different risk factors for PVT have been reported, such as decreased portal flow velocity (PBFV) and parameters related with severity of portal hypertension. However, most of these studies are retrospective and only a discrete number of parameters potentially implicated in PVT development were evaluated. The aim of the current study is to evaluate the incidence and risks factors for non-tumoral PVT development in a large prospective cohort of patien