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9mg QE/g. Acute toxicity evaluation resulted in a LD of 3807.88mg/kg. For carrageenan-induced paw edema test, IsAE in both doses (20 and 100mg/kg) reduced the edema in 83.93%. IsAE reduced nitric oxide (NO) production and leucocytes migration to peritonitis inflammation site and at a concentration of 0.5mg/mL showed also inhibition of protein denaturation similar to indomethacin in the same concentration. IsAE inhibited in 72.60% the number of contortions in writhing test. In formalin test, IsAE was also efficient, but showed results only