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Typical yearly CO2 emissions of DPIs and pMDIs had been computed in two situations present and a hypothetical scenario involving a switch from all pMDIs to DPIs. The effect of the turn on clinical outcomes was also evaluated. The total worth of CO2-eq/year because of DPIs and pMDIs reports for 0.0056per cent and 0.0909%, respectively, of total emissions in Spain. In the event of a conversion of most pMDIs to DPIs, except those for relief medicine, these percentages will be 0.0076% and 0.057