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In the subset analysis of T≥3cm with positive extrathyroidal extension (n=127), the lateral compartment RFS rate of the pLND group was significantly better (p0.01) than that of the non-pLND group (p0.01). In this subset, pLND reduced recurrence to the lateral compartment by 20.7% during the 5-year follow-up. However, pLND did not improve distant RFS. pLND significantly improved lateral node RFS in patients having PTC ≥3cm with significant extrathyroidal extension. For such patients, pLND at initial surgery may be considered to
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