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The purpose of this study was to describe medical device-related pressure injuries (MDRPIs) in hospitalized pediatric patients. A prospective, descriptive study. The sample comprised 625 patients cared for in 8 US pediatric hospitals. Participants were aged preterm to 21 years, on bed rest for at least 24 hours, and had a medical device in place. Two nursing teams, blinded to the other's assessments, worked in tandem to assess pressure injury risk, type of medical devices in use, and preventive interventions for each medical device. The