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To evaluate radiomic features extracted from standard static images (20-40min p.i.), early summation images (5-15min p.i.), and dynamic [ F]FET PET images for the prediction of TERTp-mutation status in patients with IDH-wildtype high-grade glioma. A total of 159 patients (median age 60.2years, range 19-82years) with newly diagnosed IDH-wildtype diffuse astrocytic glioma (WHO grade III or IV) and dynamic [ F]FET PET prior to surgical intervention were enrolled and divided into a training (n = 112) and a testing cohort (n = 47) randomly.