https://www.selleckchem.com/pr....oducts/grazoprevir.h
Little is known about the effect of renin angiotensin aldosterone system-inhibiting (RAASi) drugs on alternative angiotensin peptides (APs) such as angiotensin 1-7 (Ang1-7), which are mediated by angiotensin-converting enzyme 2 (ACE2). Angiotensin receptor blockers (ARBs) would alter balance of APs and differences would be magnified in vitro by incubation of plasma samples with recombinant human ACE2 (rhACE2). Six cats with cardiomyopathy (CM), 8 healthy cats. Prospective open label trial. Plasma equilibrium concentrations of APs we
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