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Since the 1980s, we now have experienced the quick development of genetically modified mouse types of individual diseases. Many transgenic and knockout mice being utilized in basic and applied research, including types of neurodegenerative and neuropsychiatric problems. To assess the biological purpose of mutated genetics, contemporary practices are vital to detect alterations in behavioral phenotypes. We review the IntelliCage, a high-throughput system that is used for behavioral testing and detail by deta