https://www.selleckchem.com/products/SNS-032.html
RESULTS During a median follow-up of 6.2 years in VHA and 6.8 years in KPW, there were 7547 new dementia cases in VHA and 1090 in KPW. After IPTW, there was no association between initiation of metformin (vs no initial treatment) and incident dementia in VHA (HR = 1.04; 95% confidence interval [CI] 0.95-1.13) or KPW (HR = 0.81; 95% CI 0.51-1.28). Results did not differ by age, baseline HbA1c, or race. CONCLUSIONS Results do not support initiating metformin earlier to prevent cognitive decline and, thus, may dampen enthusiasm for metform
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