https://www.selleckchem.com/
The current studies compared ProHeart 12, Heartgard Plus and Interceptor Plus for preventive efficacy against JYD-34, a macrocyclic lactone (ML)-resistant strain of Dirofilaria immitis in dogs. In two studies, each using 24 adult beagles, dogs were allocated to four treatment groups (n = 6) placebo-treated control; ProHeart 12 as per label (0.5mg/kg moxidectin); Heartgard Plus (HGP) as per label (minimum 6µg/kg ivermectin); and Interceptor Plus (INP) as per label (minimum 0.5mg/kg milbemycin oxime). In both studies, ProHeart 12 was administered as a single