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Making use of an miRNA microarray, it had been discovered that 24 miRNAs had been upregulated and 14 miRNAs had been downregulated compared to the undifferentiated cells, and miR‑29b‑3p (miR‑29b) ended up being chosen for further experiments. Practical experiments revealed that the upregulation of miR‑29b by agomir‑29b significantly enhanced alkaline phosphatase (ALP) activity and the mineralization of extracellular matrix (ECM), and led to an increase in the mRNA