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Medication release kinetics had been assessed in a quasi-stationary release model, using high performance liquid chromatography every 24 h for 15 times. OUTCOMES Five electrode arrcation for medical used in cochlear implantation. The chemotherapeutic effectiveness of paclitaxel against hypoxic tumors is generally unsatisfactory, that is partially as a result of the so-called hypoxia-induced medication resistance. The system of hypoxia-induced resistance is mostly related to hypoxia-inducible factor 1α (HIF-1α)