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How Does ADHD Medication Work? Many people find that ADHD medications help them focus, concentrate and control their impulsive behavior. It can be a long process to determine the appropriate medication and dose for each person. Certain medications can affect children's sleeping patterns. If they're sleeping better than before it's likely a good sign that the drugs are working. 1. Stimulants Stimulants are among the most commonly prescribed prescription drugs that doctors use to treat ADHD. They increase the levels of certain neurotransmit