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8%) and abnormaltities of the musculosceletal system including diaphragmatic hernias (n = 18; 8.6%), as reflected by the ICD-10-categories "Congenital malformation of the central nervous system", "Other congenital malformations" and "Chromosomal abnormalities". No changes were observed with regards to maternal age (30.1 ± 5.9 vs. 31.0 ± 6.0years; p = 0.315) nor frequency of assisted reproductive technologies (7.0% vs. 8.5%; p = 0.55. Despite a 2.5-fold increase in incidence of late TOPs, no epidemiological changes in maternal or fetal
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