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By molecular docking, we recognize the operating causes associated with the discussion as electrostatic discussion, hydrogen bonds and van der Waals power. The dissociation price constants (kd) of azilsartan, candesartan, valsartan and olmesartan to AT1R were 0.01138 ± 0.003, 0.05142 ± 0.003, 0.07547 ± 0.004 and 0.01310 ± 0.005 min-1 by peak profiling assay. Evaluating with your variables, puerarin and rosmarinic acid delivered reduced affinity (KA 0.12 × 104 and 1.5 × 1
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