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us dosing cohort, a high percentage of baseline tumor-infiltrating lymphocytes (10%) was associated with higher ORR and favorable PFS (p=0.029, 0.054, respectively). Conclusions The ORR by this chemo-free regimen was dramatically higher than previously reported ORR by anti-PD-1/PD-L1 antibody or apatinib monotherapy. Camrelizumab combined with apatinib demonstrated favorable therapeutic effects and a manageable safety profile in patients with advanced TNBC. Trial registration number NCT03394287.Background It is now recognized that