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Expressions of approximately 100 genes, including the major intrinsic protein of the lens fiber (Mip and Aquaporin , deoxyribonuclease II beta (Dnase2, heat shock protein B1 (HspB1), and crystallin γ (γCry) B, C, and F, were found to be significantly downregulated (0.07-0.5-fold) in rat LECs derived from cataract lenses compared to that in noncataractous lenses (control). Thus, our study was aimed at identifying the gene expression patterns during cataract formation in SCRs, which may be responsible for cataractogenesis in SCR. We
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