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This is the first genomic characterization of a metastatic tumor to the sella and reports potential genetic insight, implicating and mutations, into the pathophysiology of sellar metastasis from primary systemic tumors. This is the first genomic characterization of a metastatic tumor to the sella and reports potential genetic insight, implicating PTCH1 and BCOR mutations, into the pathophysiology of sellar metastasis from primary systemic tumors. Pneumocephalus, the presence of gas or air within the intracranial cavity, is a common finding