https://www.selleckchem.com/pr....oducts/TG100-115.htm
Despite advances in multimodal approach for rectal cancer, treatment-related side effects remain an important issue. From this perspective, a prospective trial was performed to investigate the feasibility of modulated electro-hyperthermia (mEHT) as a concomitant boost to preoperative chemoradiation in locally advanced rectal cancer. Seventy-six patients with cT3-4 or cT2N+ rectal cancer were enrolled consecutively. Whole pelvis radiotherapy of 40 Gy was delivered with 2-Gy daily fraction. mEHT with 13.56 MHz frequency was boosted on a