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Hierarchical clustering evaluation for the five genes found three groups of AML clients. The cluster1 AML customers were associated with lower cytogenetics risk than cluster2 or 3 clients, and much better prognosis than cluster3 patients (P values 0.05 for several situations, fisher precise test or log-rank test). The gene panel comprising CALCRL, DOCK1, PLA2G4A, FCHO2 and LRCH4 as well as the risk score may offer novel prognostic biomarkers and classification of AML clients to somewhat improve ou